海角禁区

Paul Mueller recently received the American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology Travel Award for Young Investigators. The $1000 award will be used to attend the ATVB|PVD 2015 Scientific Sessions in San Francisco in May. The award is distributed to a select number of young investigators based on the score of a submitted abstract.

A postdoctoral position is available immediately at the University of Kentucky to study the molecular mechanisms of metabolic disorders and atherosclerosis.  Our laboratory mainly focuses on the role of NF-kB (J Exp Med, 2014; Arterioscler Thromb Vasc Biol, 2012) and nuclear receptor PXR (Environ Health Perspect, 2012; Mol Pharmacol, 2013; JAHA 2014; Mol Endocrinol, 2015) in the pathogenesis of obesity and cardiovascular disease.  More details can be found at the following webpage: http://pharmns.med.uky.edu/use

Yipeng Sui from Changcheng Zhou鈥檚 laboratory recently received the American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology Travel Award for Young Investigators. The $1000 award will be used to attend the ATVB|PVD 2015 Scientific Sessions in San Francisco in May. The award is distributed to a select number of young investigators based on the score of a submitted abstract. Yipeng鈥檚 abstract is entitled 鈥淚ntestinal Pregnane X Receptor Links Xenobiotic Exposure And Hypercholesterolemia鈥�.

The 2015 Saha Awards application process is now open. 

The application process will close on Monday, June 1, 2015.

Xiang-An Li, Ph.D., of the University of Kentucky Saha Cardiovascular Research Center and Department of Pediatrics, has been awarded a $3 million grant from the National Institutes of Health to study synthetic HDL (sHDL) as a potential therapy for sepsis. Sepsis -- also called septicemia -- is a life-threatening condition caused by an overwhelming immune response to infection. Immune chemicals released by the body into the bloodstream to fight the infection trigger widespread inflammation that can damage multiple organ systems.

In 2013, as part of the Diabetes and Obesity Research Day at 海角禁区, the inaugural Fred and Marcielle de Beer Award was awarded to the de Beer鈥檚 for their contributions to the development of the Barnstable Brown Diabetes and Obesity Research Center (BBDOC) and for their long-standing research accomplishments at the University of Kentucky.  The 2014 recipient was Dr. Lisa Cassis.

 

 

Friday, February 6 is National Wear Red Day. 

Wear Red
In recognition of National Wear Red Day, Go Red for Women
asks that men and women GO RED by wearing red, living a healthy lifestyle and spreading the message
that heart diseaese is killing our mothers, daughters, sisters and friends.

Cell Metabolism 10th Anniversary Top 10 Breakthroughs in Immunometabolism. 

Now with the University of Kentucky Saha Cardiovascular Research Center, Dr. Prabhakara R. Nagareddy publication is at top of list.

Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity

Qing, H., Liu, Y., Zhao, Y., Aono, J., Jones, K. L., Heywood, E. B., Howatt, D., Binkley, C. M., Daugherty, A., Liang, Y. and Bruemmer, D. (2014), Deficiency of the NR4A Orphan Nuclear Receptor NOR1 in Hematopoietic Stem Cells Accelerates Atherosclerosis. STEM CELLS, 32: 2419鈥�2429. doi: 10.1002/stem.1747 Abstract The NR4A orphan nuclear receptor NOR1 functions as a constitutively active transcription factor regulating cellular inflammation and proliferation.

Davis FM, Rateri DL, Balakrishnan A, Howatt DA, Strickland DK, Muratoglu SC, Haggerty CM, Fornwalt BK, Cassis LA, Daugherty A. Smooth Muscle Cell Deletion of Low-Density Lipoprotein Receptor-Related Protein 1 Augments Angiotensin II-Induced Superior Mesenteric Arterial and Ascending Aortic Aneurysms. Arterioscler Thromb Vasc Biol. 2014 Nov 13. pii: ATVBAHA.114.304683.  PMID: 25395615

Abstract

Thompson JC, Jayne C, Thompson J, Wilson PG, Yoder MH, Webb N, Tannock LR. A brief elevation of serum amyloid A is sufficient to increase atherosclerosis. J Lipid Res. 2014 Nov 26. pii: jlr.M054015. PMID: 25429103.

Abstract

On Oct. 17, the Lexington Convention Center teemed with more than 200 students and scientists sharing their latest research on cardiovascular health for the 17th annual Gill Heart Institute Cardiovascular Research Day. Nigel Mackman, Ph.D., director of the McAllister Heart Institute at the University of North Carolina at Chapel Hill, presented "Hematosis, Thrombosis and Immunity," demonstrating the diverse roles of hemostasis and thrombosis in cardiovascular diseases, cancers and infections. Kathryn J.

University of Kentucky faculty, students, and postdoctoral fellows recently represented the institution at the second annual SEC Symposium, a program of the Southeastern Conference's academic initiative known as SECU, in Atlanta from Sept. 21 - 23.

Yipeng Sui was awarded the American Heart Association (AHA) Atherosclerosis Thrombosis and Vascular Biology (ATVB) Travel Award for Young Investigators. The international meeting will be held in Chicago at the upcoming American Heart Association Scientific Sessions. This award recognizes meritorious work by young investigators in training, encourages participation in the AHA Scientific Sessions, and provides a stipend to help defer travel expenses to present their work at the AHA Scientific Sessions.

Paul Mueller was awarded the American Heart Association (AHA) Atherosclerosis Thrombosis and Vascular Biology (ATVB) Travel Award for Young Investigators.  The international meeting will be held in Chicago at the upcoming American Heart Association Scientific Sessions. This award recognizes meritorious work by young investigators in training, encourages participation in the AHA Scientific Sessions, and provides a stipend to help defer travel expenses to present their work at the AHA Scientific Sessions.

Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies.
Heart. 2014 Oct 1;100(19):1498-1505. doi: 10.1136/heartjnl-2014-305648. Epub 2014 Jul 24.
Davis FM, Rateri DL, Daugherty A.
PMID:25060754

Abstract:

LEXINGTON, Ky. (Sept. 9, 2014) 鈥� The University of Kentucky has been awarded research grants totaling $1.26 million by The American Heart Association. 

The nine grants will fund research underway at the Gill Heart Institute's Saha Cardiovascular Research Center and the 海角禁区. 

Tori Stromp was awarded the Council on Cardiovascular Radiology and Intervention travel award to the upcoming American Heart Association Scientific Sessions in Chicago, IL. This award recognizes meritorious work by young investigators in training, encourages participation in the AHA Scientific Sessions, and provides a stipend to help defer travel expenses to present their work at the AHA Scientific Sessions. The award ($1,500) is distributed to a select number of young investigators based on the score of the submitted abstract.

The University of Kentucky 2014 Aortic Symposium was held September 4-6, 2014 at the University of Kentucky Chandler Medical Center.  The event was a huge success as it highlighted cutting-edge research from bench top to clinical care of those suffering from aortic diseases.   Almost 200 people attended events ranging from an Early Career Program and Networking Reception to Scientific Sessions and an Awards Dinner. 

A team of investigators has made a thought-provoking discovery about a type of cholesterol previously believed to be a "bad guy" in the development of heart disease and other conditions. Jason Meyer, a University of Kentucky M.D.-Ph.D.