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Dr. Taesik Gwag, along with Dr. Changcheng Zhou and colleagues from the Zhou lab have an article in the Journal of Hepatology entitled "Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis". Other co-authors include faculty colleagues Drs. Shuxia Wang, from our department, and R Greenberg of º£½Ç½ûÇø's Internal Medicine. The article deals with novel approaches to overcoming cardiovascular risks imparted by anti-viral therapies used in the treatment of HIV. Kudos to the Zhou Lab and colleagues!
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Study Links Smoking During Pregnancy With Increase in Obesity Later in Baby's Life

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Kudos to Dr. Anika Hartz who was named Faculty Mentor of the Week by º£½Ç½ûÇø's Office of Undergraduate Research.

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Congratulations to Dave Schnell, PhD, Adam Ghoweri, Kai Zhang and Nicole Robinson for getting their article published in the Health&Wellness November 2018 issue

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Fetal alcohol spectrum disorders are an array of conditions that can occur in a person whose mother consumed alcohol during pregnancy. Fetal alcohol syndrome (FAS), the most severe of these conditions, often results in physical abnormalities, behavioral development issues and intellectual disabilities.  

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Congratulations to Dr. Ai-Ling Lin, colleagues- Dr. Anika Hartz and DPNS students-Jared Hoffman and Lucy Yanckello on their recent articles in Scientific Reports and/or Frontiers in Aging Neuroscience!

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CONGRATULATIONS to all of the following: Dr. Lisa Cassis and colleagues (Drs. Andrew Morris, Wendy Katz, Changcheng Zhou and Kevin Pearson) – NIH Phase III Center of Biomedical Research Excellence (COBRE) Dr. Frederique Yiannikouris – a new NIH R01 Dr. Rina Plattner – renewed her R01, NIH supplement and Lloyd Foundation Dr. Zhenheng Guo – a new R01 and VA Award Dr. Barbara Nikolajczyk – 2 NIH Awards transferred Dr. Jia Luo – a new R21 and a VA Award extended Dr. Analia Loria – an NIH supplement Dr. Ai-Ling Lin – an NIH supplement Dr. Olivier Thibault – an NIH supplement Dr.
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The Phase III Center of Biomedical Research Excellence (COBRE) on Obesity and Cardiovascular Diseases (COCVD) focuses on identification of mechanisms and development of therapies that target obesity as a risk factor for cardiovascular diseases, diabetes, cancer and neurodegenerative diseases (e.g., Alzheimer’s disease). 

In its 11th year and extending into 2023, this center promotes 3 scientific core facilities and supports pilot projects that help us understand why obesity increases disease development.

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The University of Kentucky Barnstable Brown Diabetes Center held its eighth annual Obesity and Diabetes Research Day, highlighting the work of students, postdoctoral fellows and faculty from around the region. The program features presentations from nationally recognized physician-scientists, as well as researchers chosen from abstract submissions. 

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The 13th Annual Spring Conference of the University of Kentucky Center for Clinical and Translational Science (CCTS) was held April 13 at the Lexington Convention Center. While the CCTS supports research across the spectrum of diseases, this year’s conference focused on using translational science to address the opioid epidemic.

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Data from a new study led by University of Kentucky Markey Cancer Center researchers shows that repurposing drugs used to treat leukemia has promise for preventing melanoma metastasis.

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In a society that values gender equality, it's important to remember that there are differences between the sexes that directly impact health.

One area in critical need of further study is cardiovascular health. For the past four years, two junior faculty at the University of Kentucky have invested their efforts to host a symposium where outstanding scientists from º£½Ç½ûÇø and universities across the country present new scientific advances in women's heart health and explore translational cardiovascular research areas that merit further study.

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Dr. Changcheng Zhou and fellow departmental and º£½Ç½ûÇø colleagues, including Drs. Yipeng Sui, Zun Liu, Se-Yhung Park, Sean Thatcher and Phil Kern, have published in the new journal JCI Insight, a sister publication of the Journal of Clinical Investigation.

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Alzheimer's disease wreaks emotional havoc on patients who are robbed of their memories, their dignity and their lives. It’s financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by the time children born today are having children of their own.

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Dr. Lisa Cassis talks about recent
significant achievements in º£½Ç½ûÇø's research enterprise (click here).

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Recently published work by Drs. Gant, Blalock, Landfield and other colleagues was featured in The Scientist. Click here to read the story.

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Click Here to access article online